Leukemia is cancer of the blood cells. It starts in the bone marrow, the soft tissue inside most bones, where blood cells are made and causes large numbers of abnormal blood cells, called leukemia cells, to be produced and enter the bloodstream. The leukemia cells can crowd out the normal blood cells, which can lead to serious problems such as anemia, bleeding, and infections. Leukemia cells can also spread to the lymph nodes or other organs and cause swelling or pain.

Feinstein Institute researchers are making strides in understanding how normal bone marrow cells can develop into leukemia cells and how leukemia cells communicate with normal cells in the bone marrow. Major efforts are ongoing in studying a particular type of leukemia, chronic lymphocytic leukemia (CLL) to develop cutting edge treatments, better quality of care, and improved outcomes.

Feinstein Institute investigators conducting leukemia research include Steven Allen; Nicholas Chiorazzi; Richard Alan Furie; Jonathan E. Kolitz; Jeffrey M. Lipton; Johnson M. LiuKanti R. RaiBarbara Sherry and Sarah R. Vaiselbuh.